The third-seeded Bulldogs advanced to the Class 4, District 1 semifinals with a 63-47 win against fourth-seeded Ste. Genevieve at Notre Dame High School.
The Bulldogs will play at 7:45 tomorrow night against second-seeded Fredericktown.
Monday's game against Ste. Genevieve is believed to be the Bulldogs' first ever meeting with the Dragons.
Sikeston led 51-28 entering the fourth quarter and let the reserves play for most of the final frame.
"Sikeston is probably the best basketball team we've played this year," said Ste. Genevieve head coach Mark Gibson. "They shot the lights out tonight. Their record doesn't show how good they are. They've been struggling like we have, but they play in a much tougher area than we do."
The Bulldogs (6-17) buried nine 3-pointers on the night led by freshman Joe Lincoln's five 3-pointers.
Lincoln finished with a game-high 18 points.
"He was really getting squared up and had time to get his shot off," said Sikeston head coach Gregg Holifield. "Once he gets squared up he shoots a great percentage. He had some good looks and knocked down some big shots for us."
With Sikeston leading 30-16 at the half, Lincoln nailed four straight 3-pointers in the third quarter to help the Bulldogs build a sizable lead.
The Bulldogs were also able to convert several turnovers into breakway layups.
"They had a hard time handling our pressure," said Holifield. "We got up on them and did a good job of putting pressure on the basketball and they had some turnovers which gave us some easy buckets. That's something we haven't really gotten all year, with the people we play we don't get many easy buckets but we were able to get some tonight."
Sikeston led 13-9 after one quarter and extended the lead to 30-16 by halftime.
The Bulldogs' 23-point lead in the third quarter is the largest lead Sikeston has held in any game this year.
"Sikeston can flat run the floor," said Gibson. "I have six or seven guys who are in pretty good shape and five of them had their tongues hanging out by halftime. That kept us from playing any defense from there. It was tough for us to move our legs tonight because we got tired so quick."
Sikeston also had four players score in double figures in the game, which is the first time that's happened this season.
Junior Marcus McCaster had 13 points with four rebounds and three assists.
Sophomore Kash Bratcher added 12 points and senior Freddie Wiggins had 11 points, 12 rebounds and three steals.
"He was more aggressive and he played with confidence tonight, he's been struggling a little bit in that area," said Holifield.
"Tonight he just stepped up and played like he was capable of playing."
Ste. Genevieve (5-21) was led by Andy Miller's 15 points.