Brittany Ponder led the Hawks (13-7) with 20 points, and freshman Debra Hall added 12 points.
Central held visiting New Madrid County Central to just 16 points over the final three quarters in a home rout.
Courtney Schuessler led the Tigers (9-12) with 17 points, Christina Sexton had 16 and Wendi Zickfield added 13. Zickfield had 12 rebounds.
Delta moved to 19-1 with a road win.
Kayla Seabaugh led the Bobcats with 20 points, Ashley Deprow had 18, Shea Smith added 17 points and Kaci Menz had 10. Jodi Menz finished with 10 rebounds.
Kelley Hicks led Scott City (0-16) with nine points.
Perryville dropped its first conference game in a road loss.
The Pirates (14-6, 7-1) had already clinched the conference title.
Krista Miesner led Perryville with 16 points and Annette Weibrecht had 11.
Erica Michelsen led the Eagles with 16 points in a road win. Wendy Eftink added 15 points for Oran (12-8).
Cortney Glastetter led Woodland (10-12) with nine points.
Brittney Peet poured in 27 points in a home win. Jamisha Williams added 10 points for the Bravettes (10-8).
Chaffee grabbed a 15-4 lead after one quarter and coasted to a home victory.
Mindy Hendrix paced the Red Devils (9-10) with 11 points and Torie Keys added 10.
The Risco Tigers basketball team won their seventh straight on Monday night, with a Tri-County Conference win over Delta C-7 at home, 80-38.
Senior Andrew Halford led Risco with 22 points. Robert Fowler and Rodulfo Johnson each had 14 points for the Tigers.
"We got up and down the floor well tonight," said Risco head coach Brandon Blankenship. "We had a lot of layups because the guys were passing effectively and sometimes we made two or three passes and scored without the ball touching the floor."
Sophomore Sloan Richardson led Delta C-7 with 13 points and Nathan Boone chipped in with 12 points for the Chargers.
Risco (11-8, 6-2) hosts Bell City on Friday night. The Cubs are currently ranked No. 2 in Class 1.
"We have Bell City on Friday and that is going to be a tough game," said Blankenship. "We have won seven in a row and the guys have tons of confidence heading into the matchup. We will be at full strength and will go into the game not fearing anybody."