The game-winning goal for Central was on free kick after a Sikeston penalty in the Lady Tigers offensive end.
Sikeston defender Katelyn Turnbow received a penalty in Central's box, as a result, Megan Orr kicked in the free kick for the goal.
"It is real bad when you lose on a penalty kick," said Sikeston head coach Derrick Long. "That was the game winner. I tell my girls to play aggressive, it might have been a little over-aggressive in the box. They just capitalized on our mistakes."
Sikeston opened up the scoring in the first half on a goal by senior Allison Blurton at the 10:00 mark. Blurton's goal was assisted on by a nice pass from Turnbow.
The first half was a physical affair as both teams received yellow cards in the early going.
"They were committing a lot of fouls," said Cape Central coach Tom Doyle. "We weren't taking advantage. We had a decent first half, we had two open goals that we missed. They had some good opportunities in the first half as well. No. 10 (Blurton) had some good runs, she is very dangerous with the ball."
The Lady Tigers tied the game at 26:00 on a goal by junior Christina Sexton.
Sikeston had some chances to break the tie in the first half, as Blurton had two opportunities on goal for the lead.
On a breakaway, Blurton had an open look at goal but the shot went high. A second shot by Blurton went wide left and the game remained tied 1-1 at intermission.
"I thought we played toe-to-toe with them for a while," said Long. "We had just as many chances as they did. We just couldn't finish some of our shots. I have seen Ali (Blurton) and Abbi (Keefer) finish shots this weekend at Carbondale that did not go their way tonight."
The Lady Bulldogs were outshot in the half 13-5 and were at times too aggressive in their play.
"Derrick does a good job of making his players play physical," said Doyle. "Our players are not as used to that physical style of play. We try to play with a little more finesse, more passing. When you play a physical team, you have to play physical or they will eat you up."
Sikeston's aggression proved to work against them with the free kick at 61:00 and Central led 2-1.
"I thought our defense played pretty solid tonight," said Long. "The big thing was that we were getting beat to the midfield. When that happens, that puts a lot of pressure on the defense. We knew going in that they were a good team. They always have a quality program."
The Lady Bulldogs had a golden opportunity at 66:00, as Blurton worked free for a potential game-tying shot. However, Central goalie Chelsea Burns made a nice save to keep the Lady Tigers ahead.
Sikeston did not manage another legitimate shot on goal in the waning minutes and Central held on for the victory.
"Good win for us, a conference win is good anytime you can get one," said Doyle. "We knew when they beat Notre Dame that they were for real. We had to come in and play a good game. We have had two good wins in a row and hopefully we can keep rolling along."
Central outshot Sikeston in the game 19-12. Sikeston's goalie Paige Silverthorn recorded 10 saves, while Burns had 18 saves in the contest.
Central (8-3) host St. Vincent on Thursday.
Sikeston (5-7) will participate in the Lady Zizzer Classic over the weekend. The Lady Bulldogs will face host West Plains on Friday at 5 p.m.
In the junior varsity contest, Sikeston recorded their second straight win of the season with a 2-0 shutout win over Central.
Caitlin Underwood and Jordan Rodgers recorded the goals for the Lady Bulldogs. Lauren Coffee and Brittany Jenkins had the assists for Sikeston. The JV Lady Bulldogs are now 2-1 on the season.