Scoring 26 of her game-high 28 points in the second and third quarters, Childress guided the Lady Eagles to a 15-point halftime lead before holding on for a 77-63 win.
"There's a reason she's a 1,000 point scorer," NMCC head coach David Crockett said of Childress. "She knows how to score and that's what its going to take for us (to be successful).
"We have to have her scoring and other girls around her scoring too. When we do that we're a pretty good team."
With the Lady Eagles holding a three-point lead after the first frame, Childress kicked off the second quarter scoring back-to-back baskets to set off a 13-4 NMCC run in the first 2:43 minutes.
By the end of the half, Childress had collected 17 points to go along with Karen McGloson's 10 and Whitney Williams' eight to help the Lady Eagles push ahead 47-32 going into the break.
"We're picking it up on defense and just keeping at it," Childress said. "We hustled and went to the paint hard."
Coming out in the second half, the Lady Eagles continued their assault, adding to their lead until early in the fourth.
Capping a 9-0 run midway through the frame at the 3:32 mark, Childress blocked a Senath shot, collected that ball and went in for a layup to put NMCC up 59-36.
Though the Lady Lions (2-6) were able to match the Lady Eagles (8-4) nearly shot for shot the rest of the quarter, NMCC was still able to take a 71-49 advantage into the final frame.
It wasn't until after the Lady Eagles had taken their biggest lead of the night, at 77-51, that Senath started to cut away at their deficit by holding NMCC scoreless the final 6:30 minutes of the game.
Ending the game on a 12-0 run, the Lady Lions had closed back to within 14 points when Taylor Clifton scored the last bucket of the night with two seconds left.
"New Madrid County plays a really fast game and with pressure for four quarters. I thought we handled it well," Senath head coach Jamie Johnson said. "They're hard to handle and they have a lot of weapons which causes a lot of problems for us. But I thought our girls played really hard tonight."
Though happy with his team's overall effort, Crockett was a bit concerned of his team's offensive drought late in the game with his bench getting some minutes.
"We played with a good intensity for a long time," he said. "I don't like the way we finished. Some of those younger girls are getting some playing time there.
"They can't just say I'm in the game it's over because it's not. We still have to play because that's what's going to make us better."
With her 28 points against the Lady Lions, Childress now has 1,081 in her Lady Eagle career after hitting the 1,000 point mark back on Dec. 21 in NMCC's game against Kennett. She's the first player to hit the milestone for NMCC since 1999.
Second on the team was McGloson with 16 points while Williams and Rashauda Summers had 12 and 11 respectively.
"We missed a lot of shots tonight, a lot of easy shots, and we still scored 77," Crockett said. "I can't be too displeased with that. Overall, I thought the effort was pretty good, just until the very end."
For the Lady Lions, Rachel Tom had a team-high 16 points while Reagan Miller and Clifton scored 12 and 11 each.
SENATH (63) -- Taylor Clifton 11, Reagon Miller 12, Lauren Goff 2, Makenzie Crawford 8, Rachel Tom 16, Briana Kempf 4, Tori Brown 8, Allyson Lomax 2. FG 24, FT 15-22, F 12. (3-pointers: none. Fouled out: Brown.)
NMCC (77) -- Dallas Campbell 3, Amirah Ruff 6, Whitney Williams 12, Aqwanness Johnson 1, Benesha Childress 28, Karen McGloson 16, Rashauda Summers 11. FG 36, FT 4-14, F 20. (3-pointers: Ruff 1, Childers 2. Fouled out: none.)